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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT1
All Species:
49.7
Human Site:
S345
Identified Species:
99.39
UniProt:
P21579
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21579
NP_001129277.1
422
47573
S345
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Chimpanzee
Pan troglodytes
XP_001162436
418
47136
S341
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Rhesus Macaque
Macaca mulatta
XP_001083913
421
47395
S344
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Dog
Lupus familis
XP_539696
422
47627
S345
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P46096
421
47399
S344
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Rat
Rattus norvegicus
P21707
421
47380
S344
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506668
439
49264
S362
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Chicken
Gallus gallus
P47191
424
47487
S347
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696277
430
48125
S350
P
Y
Y
N
E
S
F
S
F
E
I
P
Q
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
S397
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Honey Bee
Apis mellifera
NP_001139207
434
48848
T361
P
Y
Y
N
E
S
F
T
F
E
V
P
F
E
Q
Nematode Worm
Caenorhab. elegans
P34693
441
49885
S364
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.8
98.5
N.A.
97.6
97.8
N.A.
93.3
95.2
N.A.
67.6
N.A.
54.6
61
56.9
N.A.
Protein Similarity:
100
97.1
98.8
98.5
N.A.
98.8
99
N.A.
94.5
97.4
N.A.
81.1
N.A.
66.6
73.7
69.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
80
N.A.
100
93.3
100
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
100
0
0
0
0
100
0
0
0
92
0
% E
% Phe:
0
0
0
0
0
0
100
0
100
0
0
0
92
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
100
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
100
0
92
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
100
100
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _